Brain zaps may wake up coma patients – early trial launches

NCT ID NCT07213869

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a gentle, non-invasive brain stimulation technique called alpha tACS can improve consciousness in people who have been in a vegetative or minimally conscious state for 3–12 months after a traumatic brain injury. Five adults will each receive alternating two-week periods of stimulation and no stimulation over three months. The goal is to see if the stimulation leads to measurable improvements in awareness and brain activity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial alternating current stimulation (tACS)

What this could lead to

If it works, this could point toward a new non-drug treatment to help people with disorders of consciousness regain awareness.

What could go wrong

This is a very early, tiny study (only 5 people) with no control group. The results may not apply to others, and the treatment may show no clear benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DISORDER OF CONSCIOUSNESS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic Consciousness Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Post-Intensive Care Neurorehabilitation Unit (Service de Reeducation Post-Reanimation) in Pierre Wertheimer Neurologic Hospital

    Bron, 69029, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••