New heart valve device shows promise for High-Risk patients
NCT ID NCT03613246
First seen Nov 17, 2025 · Last updated Jun 18, 2026 · Updated 23 times
Summary
This study looks at how well the ALLEGRA TAVI system works in real-world patients with severe aortic valve disease who are at high risk for surgery. Researchers tracked 346 patients to see if the device improves survival and quality of life. The goal is to control the disease and reduce symptoms, not to cure it.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clinica Mediterranea Neapel
Naples, Italy
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Heartcentre Catharina Hospital Eindhoven
Eindhoven, 5623 EJ, Netherlands
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Herz- und Gefäßzentrum Bad Bevensen
Bad Bevensen, 29549, Germany
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Hospital Alvaro Cunqueiro
Vigo, 36213, Spain
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hospital Universitario Virgen de la Victoria
Málaga, 29010, Spain
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Hospital Universitario de Salamanca
Salamanca, 37007, Spain
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Kath. Marienkrankenhaus
Hamburg, 22087, Germany
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MH Hannover
Hanover, 30625, Germany
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Morriston Hospital
Swansea, United Kingdom
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Ospedale San Raffaele
Milan, 20132, Italy
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Oulu University Hospital
Oulu, 90220, Finland
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SLK-Kliniken Heilbronn
Heilbronn, 74078, Germany
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Schuechtermann-klinik
Bad Rothenfelde, Germany
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.