Which pacemaker method works best after TAVI? new trial aims to find out

NCT ID NCT06197503

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of pacemaker settings in people who need a pacemaker after a TAVI procedure (a minimally invasive heart valve replacement). The two methods are 'physiological pacing' (which tries to mimic natural heart activation) and standard 'right ventricular pacing'. The goal is to see which method leads to better survival, heart function, and exercise ability after one year. The trial will enroll 48 participants with normal heart pumping function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Conduction system pacing (left bundle branch or His bundle pacing) versus right ventricular pacing
What this could lead to
If successful, this could show that a more natural pacing method improves heart function and quality of life after TAVI better than standard pacing.
What could go wrong
This is a small, single-center trial with only 48 participants, so results may not apply to everyone. The benefit may be small or not seen at all.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Clínic de Barcelona

    RECRUITING

    Barcelona, 08036, Spain

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