Which pacemaker method works best after TAVI? new trial aims to find out
NCT ID NCT06197503
First seen Apr 03, 2026 · Last updated Jun 22, 2026 · Updated 13 times
Summary
This study compares two types of pacemaker settings in people who need a pacemaker after a TAVI procedure (a minimally invasive heart valve replacement). The two methods are 'physiological pacing' (which tries to mimic natural heart activation) and standard 'right ventricular pacing'. The goal is to see which method leads to better survival, heart function, and exercise ability after one year. The trial will enroll 48 participants with normal heart pumping function.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, 08036, Spain
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Conduction system pacing (left bundle branch or His bundle pacing) versus right ventricular pacing
What this could lead to
If successful, this could show that a more natural pacing method improves heart function and quality of life after TAVI better than standard pacing.
What could go wrong
This is a small, single-center trial with only 48 participants, so results may not apply to everyone. The benefit may be small or not seen at all.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.