New drug targets rare gene mutation in Hard-to-Treat cancers
NCT ID NCT06533059
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times
Summary
This early-phase trial tests an experimental drug called ALTA2618 in about 110 adults whose advanced solid tumors (including breast and endometrial cancers) have a specific AKT1 E17K gene mutation. The main goals are to check the drug's safety and find the right dose. Participants must have tried other treatments first or be unable to take them.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site
RECRUITINGMineola, New York, 11501, United States
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Research Site
RECRUITINGNew York, New York, 10016, United States
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Research Site
RECRUITINGMaumee, Ohio, 43637, United States
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Research Site
RECRUITINGNashville, Tennessee, 37203, United States
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Research Site
WITHDRAWNDallas, Texas, 75230, United States
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Research Site
RECRUITINGHouston, Texas, 77030, United States
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Research Site
RECRUITINGSan Antonio, Texas, 78229, United States
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Research Site
RECRUITINGFairfax, Virginia, 22031, United States
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Research Site
RECRUITINGMadison, Wisconsin, 53792, United States
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Research Site
RECRUITINGBlacktown, New South Wales, 2148, Australia
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Research Site
RECRUITINGRandwick, New South Wales, 2031, Australia
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Research Site
RECRUITINGSouth Brisbane, Queensland, 4101, Australia
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Research Site
RECRUITINGMalvern, Victoria, 3144, Australia
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Research Site
RECRUITINGNedlands, Western Australia, 6009, Australia
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Research Site
RECRUITINGCaen, 14000, France
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Research Site
RECRUITINGDijon, 21000, France
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Research Site
RECRUITINGSaint-Herblain, 44805, France
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Research Site
RECRUITINGVillejuif, 94800, France
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Research Site
RECRUITINGKyoto, 606-8507, Japan
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Research Site
RECRUITINGMatsuyama, 791-0280, Japan
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Research Site
RECRUITINGShizuoka, 411-8777, Japan
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Research Site
RECRUITINGTokyo, 135-8550, Japan
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Research Site
RECRUITINGSeoul, 03722, South Korea
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Research Site
RECRUITINGSeoul, 05505, South Korea
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Research Site
RECRUITINGSeoul, 06351, South Korea
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Research Site
RECRUITINGSeoul, 06591, South Korea
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Research Site
RECRUITINGSeoul, 13620, South Korea
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Research Site
RECRUITINGBarcelona, 08023, Spain
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Research Site
RECRUITINGBarcelona, 08035, Spain
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Research Site
RECRUITINGBarcelona, 08908, Spain
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Research Site
RECRUITINGMadrid, 28023, Spain
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Research Site
RECRUITINGMadrid, 28040, Spain
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Research Site
RECRUITINGValencia, 46010, Spain
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Research Site
RECRUITINGChanghua, 500, Taiwan
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RECRUITINGTaipei, 100, Taiwan
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Research Site
RECRUITINGTaipei, 10449, Taiwan
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Research Site
RECRUITINGLondon, SW3 6JJ, United Kingdom
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Research Site
RECRUITINGLondon, W1G 6AD, United Kingdom
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Research Site
RECRUITINGLondon, W1T 7HA, United Kingdom
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Research Site
RECRUITINGManchester, M10 4BX, United Kingdom
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Research Site
RECRUITINGNewcastle upon Tyne, NE7 7DN, United Kingdom
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Research Site
RECRUITINGSutton, SM2 5PT, United Kingdom
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Research Site
RECRUITINGLa Jolla, California, 92093, United States
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Research Site
RECRUITINGLos Angeles, California, 90095, United States
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Research Site
RECRUITINGDenver, Colorado, 80218, United States
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Research Site
RECRUITINGSarasota, Florida, 34232, United States
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Research Site
RECRUITINGAtlanta, Georgia, 30322, United States
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Research Site
RECRUITINGBoston, Massachusetts, 02114, United States
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Research Site
RECRUITINGBoston, Massachusetts, 02215, United States
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Research Site
RECRUITINGSt Louis, Missouri, 63110, United States
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Research Site #2
RECRUITINGSan Antonio, Texas, 78229, United States
Conditions
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