Gut bacteria supplement shows promise for shedding pounds

NCT ID NCT06780007

Completed Disease control Sponsor: Wecare Probiotics Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested whether a probiotic called Akkermansia muciniphila Akk11 can help people with obesity lose weight. Over 12 weeks, 106 participants took either the probiotic or a placebo. Researchers measured changes in body mass index (BMI) and also looked at inflammation and metabolism. The goal is to see if this natural supplement could be a safe way to support weight management.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Akkermansia muciniphila Akk11 probiotic
What this could lead to: If it works, this could point toward a natural probiotic supplement to help with weight loss and improve metabolic health in people with obesity.
What could go wrong: This is a small, early-stage trial with only 106 participants. The effect may be modest, and results may not apply to everyone. As a dietary supplement, it is not a substitute for lifestyle changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

28≤BMI≤35KG/M2

Contacts and locations

Locations

The First Affiliated Hospital, the Air Force Medical University

Xi'an, Shaanxi, 710032, China

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