Could your memory loss be autoimmune? new study investigates

NCT ID NCT06321588

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study looks at 300 adults with new-onset cognitive impairment to see how often certain immune system markers (neuronal synaptic antibodies) are present. Researchers aim to develop a scoring system to help diagnose autoimmune dementia more accurately. The study does not test any treatment but focuses on understanding the role of these antibodies in cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a clinical score that helps doctors identify autoimmune-related cognitive decline earlier and more accurately.

What could go wrong

This is an observational study, not a treatment trial. It may not directly change patient care, and the findings might not apply to all types of dementia.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondazione IRCCS Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, Milano, 20133, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IRCCS Istituto delle Scienze Neurologiche di Bologna

    RECRUITING

    Bologna, Bologna, 40139, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Istituto Auxologico Italiano IRCCS

    RECRUITING

    Milan, Milano, 20095, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••