Could your memory loss be autoimmune? new study investigates

NCT ID NCT06321588

Recruiting now Knowledge-focused Sponsor: Azienda Usl di Bologna Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study looks at 300 adults with new-onset cognitive impairment to see how often certain immune system markers (neuronal synaptic antibodies) are present. Researchers aim to develop a scoring system to help diagnose autoimmune dementia more accurately. The study does not test any treatment but focuses on understanding the role of these antibodies in cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a clinical score that helps doctors identify autoimmune-related cognitive decline earlier and more accurately.
What could go wrong: This is an observational study, not a treatment trial. It may not directly change patient care, and the findings might not apply to all types of dementia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE IMPAIRMENT DEMENTIA

Contacts and locations

Locations

Fondazione IRCCS Istituto Neurologico Carlo Besta
RECRUITING

Milan, Milano, 20133, Italy
IRCCS Istituto delle Scienze Neurologiche di Bologna
RECRUITING

Bologna, Bologna, 40139, Italy
Istituto Auxologico Italiano IRCCS
RECRUITING

Milan, Milano, 20095, Italy

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