Tiny study tests MRI-Guided radiation for tough prostate cancers

NCT ID NCT03967080

Completed Knowledge-focused Sponsor: East and North Hertfordshire NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This small study looked at whether special MRI scans can help doctors adjust radiation treatment for high-risk prostate cancer. Only 5 men took part, all with aggressive cancer. The goal was to see if the MRI method was reliable enough to guide changes in radiation doses. Because it was so small, the results are just a first step and don't prove the approach works yet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: adaptive radiotherapy guided by multiparametric MRI
What this could lead to: If successful, this approach could help doctors adjust radiation doses to target tumors more precisely in high-risk prostate cancer.
What could go wrong: This was a very small feasibility study with only 5 participants, so results may not apply broadly. The approach is still experimental and needs much larger trials.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

East and North Hertfordshire NHS Trust

Northwood, Middlesex, HA6 2RN, United Kingdom

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