Smart radiation: MRI helps target head and neck cancer, spare healthy tissue
NCT ID NCT06137274
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing whether using MRI scans to adjust radiation therapy can better protect healthy organs in people with head and neck cancer. The study will enroll 35 patients who will receive standard intensity-modulated radiotherapy, but with a personalized boost guided by MRI. The main goal is to see if this approach reduces radiation dose to nearby structures like salivary glands and the throat by at least 7.5% compared to standard planning.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Intensity-modulated radiotherapy (IMRT) with MRI guidance
What this could lead to
If successful, this approach could reduce radiation damage to healthy tissues, potentially lowering side effects like dry mouth and swallowing problems.
What could go wrong
This is a small, early-phase trial (35 people) testing feasibility, not yet proven to improve outcomes. The technique may not work for all patients or may not reduce side effects as hoped.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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