Brain pacemaker that learns: new trial aims to personalize Parkinson's treatment
NCT ID NCT03815656
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new approach to deep brain stimulation (DBS) for people with Parkinson's disease. Instead of the usual single electrode, researchers are placing electrodes in two brain areas and using a system that adjusts stimulation based on real-time brain signals. The goal is to see if this 'adaptive' DBS can better control symptoms like tremors and stiffness. The trial involves 46 participants who are already scheduled for DBS surgery and will be followed for up to 6 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
deep brain stimulation (DBS) device
What this could lead to
If successful, this could lead to more effective, personalized DBS therapy that adapts in real time to brain signals, potentially improving symptom control for Parkinson's patients.
What could go wrong
This is an early-stage study with only 46 participants, and adaptive DBS is still experimental. It may not work better than standard DBS, and there are surgical risks from electrode implantation.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Duke University Medical Center
Durham, North Carolina, 27710, United States