Experimental immune therapy for childhood brain cancer shows early safety signals
NCT ID NCT03334305
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tested whether a personalized vaccine made from a child's own tumor could train their immune system to fight high-grade gliomas. The treatment involved giving back activated immune cells (T-cells) and dendritic cell vaccines after chemotherapy. Only 5 children received the therapy before the study was stopped early, but researchers were able to check for safety and immune responses.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's National Hospital
Washington D.C., District of Columbia, 20010, United States
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Children's of Alabama at UAB
Birmingham, Alabama, 35233, United States
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UF Health Shands Children's Hospital
Gainesville, Florida, 32608, United States