Could a simple blood injection ease knee arthritis pain?

NCT ID NCT05765266

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a single injection of platelet-rich plasma (PRP) from the ACP Max™ system can help people with knee osteoarthritis. Forty-five adults with knee pain and X-ray evidence of arthritis received either the PRP injection or a standard steroid injection. The main goal was to check safety and compare pain, stiffness, and function over 6 to 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Platelet-rich plasma (PRP) from the ACP Max™ system

What this could lead to

If it works, this could offer a longer-lasting, safer option for knee osteoarthritis pain relief compared to steroid injections.

What could go wrong

This is a small feasibility trial with only 45 participants, so results may not apply widely. The PRP injection may not outperform the steroid or could cause side effects like pain or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AMR Knoxville

    Knoxville, Tennessee, 37920, United States

  • Spectrum Medical, Inc.

    Danville, Virginia, 24541, United States

  • The Center for Clinical Research

    Winston-Salem, North Carolina, 27103, United States