Blood pressure drug may extend pregnancy in preeclampsia

NCT ID NCT05676476

Recruiting now Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The ACHIEVE trial is testing whether giving pregnant women with preeclampsia or high blood pressure medication to keep their blood pressure below 140/90 mmHg can safely prolong their pregnancy. The study will enroll 132 women between 23 and 35 weeks of pregnancy who have mild forms of these conditions. The goal is to see if this approach can delay delivery and reduce health problems for both mother and baby.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: antihypertensive medication
What this could lead to: If successful, this could show that tighter blood pressure control helps women with preeclampsia stay pregnant longer, potentially reducing complications for both mother and baby.
What could go wrong: This is a relatively small trial (132 participants) and results may not apply to all cases. The intervention only manages symptoms, not the underlying condition, and there are always risks with medication during pregnancy.

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced hypertensive disorder preeclampsia Toxemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GESTATIONAL HYPERTENSION HYPERTENSIVE DISORDER OF PREGNANCY PREECLAMPSIA

Contacts and locations

Locations

Oschner
RECRUITING

New Orleans, Louisiana, 70115, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States

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