New Fat-Based filler could permanently fix body defects

NCT ID NCT03544632

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new injectable material called acellular adipose tissue (AAT) to repair modest soft tissue defects on the trunk, such as those from injury or surgery. Fifteen adults received one or more injections of AAT, which is made from donated fat cells stripped of their living components. The goal was to see if the filler is safe and stays in place to improve appearance over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

acellular adipose tissue (AAT)

What this could lead to

If it works, this could offer a permanent, natural-looking option for repairing soft tissue defects without needing the patient's own fat or repeated injections.

What could go wrong

This is a small, early-phase study with only 15 people, so results may not apply to everyone. The injection is permanent, so any complications like infection or poor cosmetic outcome would be difficult to reverse.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

injury Soft Tissue Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins University School of Medicine

    Baltimore, Maryland, 21287, United States