New Fat-Based filler could permanently fix body defects

NCT ID NCT03544632

Completed Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new injectable material called acellular adipose tissue (AAT) to repair modest soft tissue defects on the trunk, such as those from injury or surgery. Fifteen adults received one or more injections of AAT, which is made from donated fat cells stripped of their living components. The goal was to see if the filler is safe and stays in place to improve appearance over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: acellular adipose tissue (AAT)
What this could lead to: If it works, this could offer a permanent, natural-looking option for repairing soft tissue defects without needing the patient's own fat or repeated injections.
What could go wrong: This is a small, early-phase study with only 15 people, so results may not apply to everyone. The injection is permanent, so any complications like infection or poor cosmetic outcome would be difficult to reverse.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SOFT TISSUE INJURIES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

injury Soft Tissue Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOFT TISSUE INJURIES TRAUMA

Contacts and locations

Locations

Johns Hopkins University School of Medicine

Baltimore, Maryland, 21287, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.