Could a simple Under-the-Tongue spray protect kidneys?
NCT ID NCT07187713
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a liquid medication called ACE Reno, taken under the tongue four times daily for 12 weeks, in 300 adults with chronic kidney disease from diabetes, high blood pressure, autoimmune disorders, or other causes. The goal is to see if it safely reduces protein in the urine and helps stabilize kidney function. Researchers hope the peptides in ACE Reno can target multiple pathways that drive kidney damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ACE Reno (a solution of bioactive peptides and amino acids taken under the tongue)
- What this could lead to
- If successful, this could offer a new treatment option to slow kidney disease progression and reduce protein leakage in patients with various causes of chronic kidney disease.
- What could go wrong
- This is a Phase 4 trial, but results may not apply to all kidney disease types. The treatment effect may be modest, and long-term benefits or risks beyond 12 weeks are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
British Centre For Regenerative medicine BCRMED Global
RECRUITINGGiza, GZ, 12311, Egypt
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