5-Day brain zapping shows promise for stubborn depression

NCT ID NCT04684706

First seen Jan 24, 2026 · Last updated May 21, 2026 · Updated 14 times

Summary

This study tests a faster way to treat depression that hasn't improved with standard treatments. Instead of 6 weeks of daily brain stimulation, participants receive 10 sessions per day for 5 days. The goal is to quickly reduce depressive symptoms in 40 adults aged 18-70 with treatment-resistant depression.

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Contacts and locations

Locations

  • Center for Neuromodulation in Depression and Stress

    Philadelphia, Pennsylvania, 19104, United States

  • Department of Interventional Psychiatry, University of California San Diego

    La Jolla, California, 92093, United States

Conditions

Explore the condition pages connected to this study.