New hope for hard-to-treat brain lymphoma: targeted drug shows promise in early trial

NCT ID NCT04906902

First seen Feb 28, 2026 · Last updated Apr 30, 2026 · Updated 6 times

Summary

This study tests a drug called acalabrutinib in people whose central nervous system lymphoma has returned or not responded to prior therapy. The goal is to find the safest dose and see how well it shrinks tumors. About 49 adults will take part in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.