New hope for brain cancer: targeted drug shows promise in early trial
NCT ID NCT04906902
First seen Feb 28, 2026 · Last updated Jun 16, 2026 · Updated 15 times
Summary
This study tests a drug called acalabrutinib in people whose central nervous system lymphoma has returned or not responded to prior therapy. The trial has two phases: first to find the safest dose, then to see how well it shrinks tumors. About 49 participants will take the drug by mouth and be monitored for side effects and response.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
Conditions
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