New hope for hard-to-treat colorectal cancer: triple-drug combo enters human trials

NCT ID NCT07244705

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new drug called ABT-301 combined with two other drugs (tislelizumab and bevacizumab) in people with advanced colorectal cancer that has not responded to at least two prior treatments. The goal is to see if the combination is safe and can shrink tumors. About 66 adults with a specific type of colorectal cancer (pMMR/non-MSI-H) will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Austin Health - Cancer Clinical Trials Centre (CCTC)

    NOT_YET_RECRUITING

    Heidelberg, Victoria, 3084, Australia

  • Chang Gung Medical Foundation, Kaohsiung Chang Gung Memorial Hospital

    NOT_YET_RECRUITING

    Kaohsiung City, 833, Taiwan

  • Chang Gung Medical Foundation, Linkou Chang Gung Memorial Hospital

    NOT_YET_RECRUITING

    Taoyuan, 333, Taiwan

  • E-Da Cancer Hospital

    NOT_YET_RECRUITING

    Kaohsiung City, 824, Taiwan

  • Greenslopes Private Hospital - Cyril Gilbert Cancer Centre

    NOT_YET_RECRUITING

    Greenslopes, Queensland, 4120, Australia

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    NOT_YET_RECRUITING

    Kaohsiung City, 807, Taiwan

  • Linear Clinical Research

    NOT_YET_RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • Liverpool Cancer Therapy Centre

    NOT_YET_RECRUITING

    Liverpool, New South Wales, 2170, Australia

  • Macquarie University Hospital (MUH)

    NOT_YET_RECRUITING

    Macquarie Park, New South Wales, 2109, Australia

  • Monash University - Faculty of Medicine, Nursing and Health Sciences

    NOT_YET_RECRUITING

    Clayton, Victoria, 3800, Australia

  • National Cheng Kung University Hospital

    NOT_YET_RECRUITING

    Tainan, 701, Taiwan

  • National Taiwan University Hospital - Cancer Center

    NOT_YET_RECRUITING

    Taipei, 100, Taiwan

  • Scientia Clinical Research

    RECRUITING

    Randwick, New South Wales, 2031, Australia

  • Taipei Medical University Shuang Ho Hospital, Ministry of Health and Welfare

    NOT_YET_RECRUITING

    New Taipei City, 235, Taiwan

  • The Queen Elizabeth Hospital (TQEH)

    NOT_YET_RECRUITING

    Woodville South, South Australia, 5011, Australia