New hope for hard-to-treat colorectal cancer: triple-drug combo enters human trials
NCT ID NCT07244705
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new drug called ABT-301 combined with two other drugs (tislelizumab and bevacizumab) in people with advanced colorectal cancer that has not responded to at least two prior treatments. The goal is to see if the combination is safe and can shrink tumors. About 66 adults with a specific type of colorectal cancer (pMMR/non-MSI-H) will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Austin Health - Cancer Clinical Trials Centre (CCTC)
NOT_YET_RECRUITINGHeidelberg, Victoria, 3084, Australia
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Chang Gung Medical Foundation, Kaohsiung Chang Gung Memorial Hospital
NOT_YET_RECRUITINGKaohsiung City, 833, Taiwan
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Chang Gung Medical Foundation, Linkou Chang Gung Memorial Hospital
NOT_YET_RECRUITINGTaoyuan, 333, Taiwan
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E-Da Cancer Hospital
NOT_YET_RECRUITINGKaohsiung City, 824, Taiwan
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Greenslopes Private Hospital - Cyril Gilbert Cancer Centre
NOT_YET_RECRUITINGGreenslopes, Queensland, 4120, Australia
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Kaohsiung Medical University Chung-Ho Memorial Hospital
NOT_YET_RECRUITINGKaohsiung City, 807, Taiwan
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Linear Clinical Research
NOT_YET_RECRUITINGNedlands, Western Australia, 6009, Australia
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Liverpool Cancer Therapy Centre
NOT_YET_RECRUITINGLiverpool, New South Wales, 2170, Australia
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Macquarie University Hospital (MUH)
NOT_YET_RECRUITINGMacquarie Park, New South Wales, 2109, Australia
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Monash University - Faculty of Medicine, Nursing and Health Sciences
NOT_YET_RECRUITINGClayton, Victoria, 3800, Australia
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National Cheng Kung University Hospital
NOT_YET_RECRUITINGTainan, 701, Taiwan
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National Taiwan University Hospital - Cancer Center
NOT_YET_RECRUITINGTaipei, 100, Taiwan
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Scientia Clinical Research
RECRUITINGRandwick, New South Wales, 2031, Australia
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Taipei Medical University Shuang Ho Hospital, Ministry of Health and Welfare
NOT_YET_RECRUITINGNew Taipei City, 235, Taiwan
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The Queen Elizabeth Hospital (TQEH)
NOT_YET_RECRUITINGWoodville South, South Australia, 5011, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Chemo holidays put to the test: can scheduled breaks beat continuous treatment for advanced colorectal cancer?