COLORECTAL CANCER (DIAGNOSIS)

This study tests a new drug, ABT-301, combined with two existing cancer drugs (tislelizumab and bevacizumab) in people with advanced colorectal cancer that hasn't responded to at least two prior treatments. The goal is to find the safest dose and see if the combination shrinks tu…

This study aims to confirm how well the ColoSense stool test works at detecting colorectal cancer and precancerous growths. It will enroll 12,500 adults aged 45 and older who are due for a colonoscopy. Participants will provide a stool sample for the ColoSense test and then under…

This study tests whether a nerve block (superior hypogastric plexus block) can help people recover better after laparoscopic surgery for colorectal cancer. About 170 adults having this surgery will be randomly assigned to receive the nerve block or not. The main goal is to see if…

This study looks at whether eating a high-fiber diet (over 21 grams per day) can change gut bacteria and improve the immune system in people with solid tumors like colorectal cancer. About 25 participants will follow this diet to see if it is safe and helps with treatment respons…

This study tests whether art therapy, delivered through virtual reality glasses or in person, can help reduce anxiety and improve sleep and well-being in people with colorectal cancer who are receiving chemotherapy. 78 patients will be split into three groups: virtual art therapy…

This study looks at how well a virtual oncology program works for veterans with lung, colorectal, prostate, or breast cancer. About 1,800 veterans will take part to see if using video or phone visits improves their care and lowers costs. The goal is to learn how to make cancer ca…

This study looks at whether a small drop of blood from a finger-prick device can reliably detect tumor DNA in patients with colorectal cancer that has spread to the liver. Researchers will compare results from the finger-prick sample to a standard blood draw from a vein. If succe…