Could a rheumatoid arthritis drug ease knee osteoarthritis pain?

NCT ID NCT02993029

Recruiting now Symptom relief Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether 99Tc-MDP (Yunke), a drug already used for rheumatoid arthritis, can reduce pain and stiffness in people with knee osteoarthritis. It compares the drug to celecoxib, a common painkiller. The trial will enroll 40 participants and measure changes in pain, joint function, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 99Tc-MDP (Yunke) and celecoxib (Xile Bao)
What this could lead to: If it works, this could offer a new treatment option for knee osteoarthritis that may improve pain, stiffness, and joint function.
What could go wrong: This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. It is also not yet known if 99Tc-MDP is better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TREATMENT OUTCOME

Contacts and locations

Locations

Department of Nuclear Medicine, Tenth People's Hospital of Tongji University
RECRUITING

Shanghai, Shanghai Municipality, 200072, China

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