New scan could reveal hidden prostate cancer

NCT ID NCT03181867

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times

Summary

This study tests a radioactive tracer called 18F-DCFPyL to see if it can better detect prostate cancer that has spread outside the prostate or come back after treatment. About 360 men with high-risk or recurrent prostate cancer will get an injection of the tracer and then have a PET/CT scan. The goal is to improve imaging accuracy so doctors can make better treatment decisions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-DCFPyL (a radioactive tracer for PET/CT scans)

What this could lead to

If successful, this could lead to a more accurate imaging method to find where prostate cancer has spread or returned, helping doctors choose the right treatment.

What could go wrong

This is a Phase 2 trial with 360 participants, so results are still early. The tracer may not detect all cancer sites, and its benefit over current scans is not yet proven.

Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate cancer prostate carcinoma prostate neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.