Could storing lungs at 10°C improve transplant outcomes?
NCT ID NCT05898776
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether storing donor lungs at 10°C instead of the usual ice cooler reduces severe lung injury after transplant. About 300 people receiving a lung transplant will be randomly assigned to one of two storage methods. The main goal is to see if the 10°C method is at least as safe as the standard ice method.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
10°C lung preservation using X°Port Lung Transport Device
What this could lead to
If this works, it could reduce the risk of severe lung injury after transplant and allow safer, longer storage times for donor lungs.
What could go wrong
This is a non-inferiority trial, so it may only show that 10°C storage is as safe as ice, not better. The results may not apply to all donor lungs.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centre Hospitalier Universitaire Vaudois (CHUV)
Lausanne, Switzerland
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Centre hospitalier de l'Université de Montréal
Montreal, Quebec, H2X0A9, Canada
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Corewell Health Research Institute
Grand Rapids, Michigan, 49503, United States
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Dignity Health (St. Joseph's Hospital and Medical Center)
Phoenix, Arizona, 85050, United States
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital Universitario Puerta de Hierro-Majadahonda
Madrid, Spain
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Medical University of Vienna
Vienna, Austria
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St Vincent's Hospital Sydney Limited
Sydney, New South Wales, 2010, Australia
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The Saint Joseph Hospital Foundation (Hôpital Marie Lannelongue)
Paris, 75014, France
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University Health Network (Toronto General Hospital)
Toronto, Ontario, M5G 2C4, Canada
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University Hospital Zurich
Zurich, Switzerland
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University Hospitals Leuven
Leuven, Belgium
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University of California San Francisco
San Francisco, California, 94143, United States
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University of Miami
Coral Gables, Florida, 33146, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States