New registry aims to boost lung transplants by reconditioning donor lungs
NCT ID NCT05101460
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This registry follows 315 people who received a lung transplant after the donor lung was treated with the XVIVO Perfusion System, a device that keeps lungs warm and oxygenated outside the body. Researchers are tracking survival and lung function for up to 5 years to see how well these lungs perform long-term. The goal is to gather real-world data on safety and effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
XVIVO Perfusion System with STEEN Solution
What this could lead to
If successful, this could confirm that EVLP helps more donor lungs become usable for transplant, potentially increasing the number of lung transplants available.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove EVLP is better than standard care. Results may not apply to all transplant centers.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States