Women's College Hospital

This study tests whether nitrous oxide, commonly known as laughing gas, can reduce symptoms of depression in people whose depression has not improved with standard treatments. About 120 adults aged 18 to 65 with treatment-resistant depression will receive either the gas or a plac…

This study compares two surgical methods (single-row vs. double-row repair) for people with chronic Achilles tendon pain that hasn't improved with non-surgical treatments. About 166 adults aged 18 to 75 will be randomly assigned to one of the two procedures. The goal is to see wh…

This study tests if using a safe, non-invasive brain stimulation device at home before and after knee replacement surgery can help manage pain and lower the risk of long-term pain. About 70 adults scheduled for knee replacement will use the device or a sham version. The main goal…

This study tests whether a specific nerve block, called the femoral articular branch block, can reduce pain and the need for opioid painkillers after hip replacement surgery. Half of the 95 participants will receive the nerve block, and the other half will receive a placebo. The …