Western University, Canada

This study looks at whether supervised exercise and the diabetes drug semaglutide, alone or together, can improve thinking and brain health in older adults with type 2 diabetes. About 164 people aged 65 and older will take part. They will be assigned to exercise training, a contr…

This study will test whether a 12-week group exercise program is safe and practical for people with osteoporosis who have recently had a fracture. One hundred participants will attend twice-weekly classes and undergo bone scans and interviews. The goal is to see if this type of p…

This study compares two surgical techniques—labral repair and labral reconstruction—for treating hip impingement in people over 40. Researchers will enroll 220 participants to see which approach better improves hip function and pain. The goal is to determine if a larger trial is …

This study will test a once-daily triple inhaler (Trelegy) in 60 adults with moderate-to-severe COPD who still have breathlessness or poor health despite current treatment. Researchers will use a special MRI (129-Xenon) to measure how well air moves through the lungs before and a…

This study tests whether small changes—like playing calming music, showing a relaxing video, or giving numbing gel at the right time—can reduce pain and anxiety during a bladder cancer exam or treatment. About 378 adults with bladder cancer will be randomly assigned to receive on…

This study tests a mobile app designed for people with functional movement disorder (FMD), a condition where the brain doesn't send movement signals properly. The app lets users record symptoms, stress, and mood as they happen, and offers simple self-help tools. Ten adults with F…

This study will follow 200 people with severe asthma and healthy volunteers over 2 years to see if biologic therapy can reverse airway and blood vessel damage. Participants will undergo imaging, lung function tests, and symptom checks. The goal is to understand if clinical remiss…

This study looks at how people with functional movement disorders (FMD) experience a sense of control over their actions. Researchers will measure how quickly participants respond when asked if they caused an action, using a computer task. The goal is to develop a more objective …