Cheaper ketamine pills could expand depression treatment
NCT ID NCT07683988
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study compares how the body absorbs ketamine when taken as a pill versus under the tongue in people with major depression. Ten adults will try both forms in a crossover design, with blood samples measuring drug levels. The goal is to find safe, effective doses for these cheaper, easier-to-use alternatives to IV ketamine.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketamine
- What this could lead to
- If successful, this could point toward more affordable and accessible ketamine treatments for depression, using pills or drops instead of IV infusions.
- What could go wrong
- This is a very small, early-phase pilot study with only 10 participants. It measures drug levels, not depression improvement, so it may not lead to a proven treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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