Va Office Of Research And Development
Clinical trials sponsored by Va Office Of Research And Development, explained in plain language.
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VA hunts for better way to stop dangerous gut infection from coming back
Disease control TerminatedThis study aimed to find the best antibiotic treatment to stop C. difficile (C. diff) infections from coming back. It compared three different antibiotic plans in over 300 veterans who had already suffered one or two recurrences of this serious gut infection. The goal was to see …
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Apr 02, 2026 02:11 UTC
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Brain stimulation and sound cues tested to help SCI patients regain hand function
Disease control TerminatedThis study aimed to help people with chronic spinal cord injuries in the neck improve their ability to grasp objects. Researchers tested whether combining gentle, non-invasive brain stimulation and specific sound cues with hand training could strengthen the brain and spinal cord …
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Could a grape seed pill help shrink tumors before surgery?
Disease control TerminatedThis study tested whether a special, highly absorbable form of grape seed extract could help treat early-stage lung cancer when taken for 2-3 weeks before surgery. Researchers wanted to see if the extract was safe, if patients could tolerate it without delaying their operation, a…
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Brain scan could end guesswork for PTSD meds
Diagnosis TerminatedThis study tested whether a simple brainwave test could predict which veterans with PTSD or depression would respond well to common antidepressant medications (SSRIs). Researchers measured participants' brain responses to sounds before starting medication, then tracked their symp…
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Diagnosis
Last updated Mar 30, 2026 14:35 UTC
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New app aims to help veterans at risk of suicide by teaching them to recognize their feelings
Symptom relief TerminatedThis study tested a new program for veterans with serious mental illness who are at risk of suicide. The program combined weekly group education with a smartphone app designed to help people better recognize and understand their own emotions, a skill linked to lower suicide risk.…
Phase: PHASE1 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 02, 2026 02:11 UTC
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VA tests home care for veterans choosing to forgo dialysis
Symptom relief TerminatedThis small pilot study tested whether a home-based care program was practical and acceptable for veterans with advanced kidney disease who chose not to start dialysis. The program aimed to support quality of life and manage symptoms through home visits and coordinated care. Resea…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Brain scans may predict who benefits from 'Social Hormone' for schizophrenia
Symptom relief TerminatedThis study tested whether oxytocin, a hormone involved in social bonding, could help improve social functioning in veterans with schizophrenia. Researchers used brain scans to see how oxytocin affected brain activity and tried to predict which individuals might benefit from a thr…
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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Can a faster therapy fix veteran sleep problems?
Symptom relief TerminatedThis study tested whether a shorter, 4-session version of Cognitive-Behavioral Therapy for Insomnia (CBT-I) works as well as the standard 6-session version for veterans. It aimed to see if the brief therapy could improve sleep, daily function, and mental health symptoms just as e…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Phone therapy trial aims to curb veteran suicide crisis
Symptom relief TerminatedThis study tested whether adding a brief problem-solving therapy to standard suicide safety planning could better reduce suicidal thoughts in older veterans. It enrolled 117 veterans aged 55+ who had suicidal thoughts and a diagnosis like depression, anxiety, or PTSD. The therapy…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Can short bursts of low oxygen help heal spinal cords?
Knowledge-focused TerminatedThis early-stage research aims to understand if a new therapy can help improve arm and hand movement after a neck-level spinal cord injury. The therapy involves brief, repeated periods of low-oxygen breathing combined with hand exercises. The study first tests this approach in ra…
Phase: EARLY_PHASE1 • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists probe dangerous blood pressure spike from common anemia drug
Knowledge-focused TerminatedThis study aimed to understand why a drug called erythropoietin (EPO), used to treat anemia, often raises blood pressure in people with chronic kidney disease. Researchers compared blood pressure changes and blood vessel function in a small group of patients who received EPO imme…
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC