University Of Vermont Medical Center

This study is for adults with a common type of skin cancer (squamous cell carcinoma) on the head or neck. After surgery to remove the cancer, some high-risk patients will get a short course of radiation (5 treatments over 2 weeks) to see if it works as well as the standard longer…

This study is testing whether people with brain metastases from lung cancer or other solid tumors can safely avoid radiation therapy if their medication (immunotherapy, targeted therapy, or chemotherapy) shrinks or stabilizes the brain tumors. About 45 participants will get a bra…

This study tests the drug apixaban to prevent blood clots in people with newly diagnosed grade 4 brain tumors (glioblastoma or astrocytoma). About 40 participants will take apixaban while receiving standard radiation and chemotherapy. The goal is to see if the drug is safe and re…

This study tests a new type of radiation therapy called HART for people whose cancer has spread. The goal is to see if it causes fewer stomach side effects than standard treatment. About 103 adults with metastatic cancer will receive HART to areas like the chest, belly, or pelvis…

This study tests whether remote nutritional counseling helps cancer patients stick to their treatment plan and feel better. 240 adults with invasive cancer starting therapy will receive either a single consultation with written materials or a more intensive program with monthly f…

This study compares intensive multi-disciplinary care (a team of specialists working together) to standard care for 40 adults with newly diagnosed brain metastases from solid tumors. The goal is to see if the team approach reduces symptom burden and helps patients better understa…

This study tests whether pyridostigmine, a drug that affects nerve signals, can help with constipation in people with Parkinson's disease. Constipation is a common and bothersome symptom that often starts years before movement problems. The study will track how often participants…

This study tests whether a short video can help people with early-stage cancer living in rural Vermont understand their disease and speak up for themselves. About 40 adults will either get the video right away or after a few months. Researchers will measure how well patients feel…