University Of Vermont
Clinical trials sponsored by University Of Vermont, explained in plain language.
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Can Low-Nicotine smokes help pregnant moms quit?
Disease control CompletedThis study looked at whether giving pregnant smokers cigarettes with very low nicotine helps them smoke less. Thirty women who were less than 25 weeks pregnant and had no college degree took part. Half smoked their usual brand, half got low-nicotine cigarettes, and researchers tr…
Phase: PHASE1, PHASE2 • Sponsor: University of Vermont • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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Cash for clean urine: pilot study tests incentives for stimulant abstinence
Disease control CompletedThis pilot study tested whether offering small financial rewards for negative urine tests could help people who use stimulants (like methamphetamine or cocaine) stay abstinent. 27 adults from a syringe exchange program took part. The experimental group could earn money for each s…
Phase: NA • Sponsor: University of Vermont • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Free meals delivered to homes boost food security and mood in opioid recovery
Disease control CompletedThis pilot study tested whether delivering pre-made meals to the homes of 50 adults with opioid use disorder could improve food insecurity. Participants who received weekly meal deliveries along with nutrition education reported better food security, fewer depression symptoms, an…
Phase: NA • Sponsor: University of Vermont • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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Pregnant smokers earn cash via app to kick the habit
Disease control CompletedThis study tested whether offering financial incentives through a smartphone app could help pregnant women quit smoking. 150 women were split into two groups: one received rewards for passing remote breath and saliva tests showing no smoking, and the other got standard care. The …
Phase: NA • Sponsor: University of Vermont • Aim: Disease control
Last updated Jun 11, 2026 12:09 UTC
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Direct injection of chemo into lung tumors shows promise in early trial
Disease control CompletedThis early-phase trial tested injecting the chemotherapy drug cisplatin directly into lung tumors during a bronchoscopy for people with early-stage non-small cell lung cancer. The goal was to find the safest dose and see how well the tumor responds. Only 6 participants were enrol…
Phase: PHASE1 • Sponsor: University of Vermont • Aim: Disease control
Last updated Jun 01, 2026 17:55 UTC
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Can talk therapy tame PTSD in opioid patients?
Symptom relief CompletedThis study looked at whether adding a type of talk therapy called prolonged exposure therapy (PET) to standard opioid addiction treatment can help reduce PTSD symptoms. 82 adults with both opioid use disorder and PTSD took part. Some got only addiction treatment, while others als…
Phase: NA • Sponsor: University of Vermont • Aim: Symptom relief
Last updated Jun 15, 2026 19:05 UTC
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Could a supplement help obese asthma patients breathe easier?
Symptom relief CompletedThis study tested whether MitoQ, a supplement that targets cell energy, can improve airway function in 47 obese adults with poorly controlled asthma. Participants took MitoQ or a placebo for 14 weeks. The main goal was to see if MitoQ reduces airway reactivity, a key asthma sympt…
Phase: PHASE1 • Sponsor: University of Vermont • Aim: Symptom relief
Last updated Jun 10, 2026 13:26 UTC
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App-Based exercise program shows promise for asthma control in obese adults
Symptom relief CompletedThis study tested a 12-week remote exercise program using a mobile app called Vitala in 20 adults with obesity and poorly controlled asthma. The main goal was to see if the program was easy to use and stick with. Researchers also checked if asthma symptoms improved during the pro…
Phase: NA • Sponsor: University of Vermont • Aim: Symptom relief
Last updated Jun 10, 2026 13:25 UTC
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Can zinc help fight sepsis? early study explores dosing
Knowledge-focused CompletedThis early-phase study looked at how the body handles zinc in people with severe sepsis, a life-threatening infection that causes organ failure. Researchers gave different doses of intravenous zinc to 40 ICU patients on breathing machines and compared them to 15 healthy volunteer…
Phase: PHASE1 • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 17, 2026 01:29 UTC
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Why do knees get weaker after surgery? new study investigates
Knowledge-focused CompletedThis study looked at why people lose muscle size and strength after total knee replacement surgery. Researchers studied 23 adults with knee osteoarthritis before and after surgery to measure muscle fiber changes and physical activity. The goal was to understand the causes of post…
Phase: NA • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:04 UTC
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Choline boosts brain activity in menopause? study reveals clues
Knowledge-focused CompletedThis study looked at how a single high dose of choline (a nutrient) changes brain activity in healthy postmenopausal women aged 50-65. Using brain scans (fMRI), researchers measured brain signals during a memory task. The goal was to understand choline's effects on the brain, not…
Phase: NA • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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Shocking recovery: electrical pulses may help seniors bounce back after lung illness
Knowledge-focused CompletedThis study tested whether using gentle electrical pulses to stimulate leg muscles (called NMES) could help older adults recover strength and mobility after being hospitalized for COPD or pneumonia. Seven participants used the device during their hospital stay and for six weeks at…
Phase: NA • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC
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Menopause brain changes may signal Alzheimer's risk
Knowledge-focused CompletedThis study looked at how menopause-related hormone changes affect brain function and Alzheimer's risk in 120 postmenopausal women aged 50-70. Researchers used memory tests and brain scans to see which women's brains coped well with hormone changes and which showed signs of future…
Phase: EARLY_PHASE1 • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:18 UTC
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New approach to CPR talks may help patients and families feel heard
Knowledge-focused CompletedThis study tested a new way for doctors to talk about CPR with seriously ill older patients and their families. About 182 patients with conditions like advanced heart failure or cancer took part. The goal was to see if this approach improved how patients and families rated the qu…
Phase: PHASE2, PHASE3 • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:05 UTC