University Of Sydney

After a kidney or kidney-pancreas transplant, the body may attack the new organ—a problem called acute T cell mediated rejection. Doctors use strong steroids to stop this, but there's no standard dose, and too much can cause serious side effects. This phase 3 trial will enroll 54…

This study tests a new way to plan radiation therapy for people with stage 3 lung cancer. The method uses CT ventilation imaging to identify and avoid the healthiest parts of the lungs during treatment. Researchers want to see if this approach helps patients maintain a better qua…

This study tests three home-based programs for people with long-term muscle or joint pain (like back pain or arthritis) who also sleep poorly. Participants will be randomly assigned to 12 months of exercise, cognitive behavioural therapy for insomnia (CBT-I), or both. The goal is…

This study is developing an AI system that tracks tumors and organs during radiation therapy without needing physical markers. Researchers will use existing patient data to train and test the AI. If it works, it could help doctors target radiation more accurately. The study invol…

This study is testing a new technology that uses x-rays to track lung tumors during radiation therapy, without needing to implant markers in the lung. About 30 people with early-stage lung cancer or a few lung metastases will take part. The goal is to see if the markerless tracki…

This pilot study tests whether using CT ventilation imaging can more accurately predict lung function after lung cancer surgery compared to the standard method. Researchers will compare predictions from CT scans with actual lung function tests in 15 surgical candidates. If succes…

This study tests whether special X-ray imaging techniques can map which parts of the lung are working best, so radiation for lung cancer can avoid those areas. Fifteen adults with stage II-IV lung cancer will get extra scans before and after their standard radiation treatment. Th…

This study is testing whether special MRI scans can identify low-oxygen (hypoxic) areas in glioblastoma, an aggressive brain cancer. Researchers will compare these scans with a standard PET imaging method in 20 participants. The goal is to see if MRI can reliably guide radiation …

This study tests a new type of CT scan that pauses during irregular breathing to get clearer images for lung cancer radiation planning. It involves 30 adults with lung cancer who will receive one extra scan during their usual treatment simulation. The goal is to see if this metho…

This study looks at images from 50 liver cancer patients who received a special dye (contrast agent) during a procedure before radiation therapy. Researchers want to see if a software program (KIM) can detect that dye in the images to better track the tumor during treatment. The …