TACKLE-IT study aims to end guesswork in transplant rejection treatment
NCT ID NCT06474273
First seen May 09, 2026 · Last updated May 12, 2026 · Updated 1 time
Summary
After a kidney or kidney-pancreas transplant, the body may attack the new organ, a problem called acute T cell rejection. Doctors use strong steroids to treat this, but the right dose is unclear, and too much can cause serious side effects. This study will test different steroid doses in 540 transplant patients to find the safest and most effective treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Auckland City Hospital
NOT_YET_RECRUITINGGrafton, Auckland, 1023, New Zealand
Contact
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Dalhousie University
NOT_YET_RECRUITINGHalifax, Nova Scotia, B3H 4R2, Canada
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John Hunter Hospital
NOT_YET_RECRUITINGLambton, New South Wales, 2305, Australia
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McGill University
NOT_YET_RECRUITINGMontreal, Quebec, H3A 0G4, Canada
Contact
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Monash Medical Centre
NOT_YET_RECRUITINGClayton, Victoria, 3168, Australia
Contact
Contact
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Prince of Wales Hospital
NOT_YET_RECRUITINGRandwick, New South Wales, 2031, Australia
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Princess Alexandra Hospital
NOT_YET_RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Queensland Children's Hospital
RECRUITINGSouth Brisbane, Queensland, 2014, Australia
Contact
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Royal Adelaide Hospital
NOT_YET_RECRUITINGAdelaide, South Australia, 5000, Australia
Contact
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Royal Perth Children's hospital
NOT_YET_RECRUITINGNedlands, Western Australia, 6009, Australia
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Royal Perth Hospital
NOT_YET_RECRUITINGPerth, Western Australia, 6000, Australia
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Sir Charles Gairdner Hospital
NOT_YET_RECRUITINGNedlands, Western Australia, 6009, Australia
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The Sydney Children's Hospital Network
NOT_YET_RECRUITINGWestmead, New South Wales, 2145, Australia
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Transplant Manitoba, adult
NOT_YET_RECRUITINGWinnipeg, Manitoba, R3A 1R9, Canada
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Transplant Manitoba, pediatric
NOT_YET_RECRUITINGWinnipeg, Manitoba, R3A 1R9, Canada
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University of Alberta
NOT_YET_RECRUITINGEdmonton, Alberta, T6G 2R3, Canada
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University of Calgary
NOT_YET_RECRUITINGCalgary, Alberta, T2N 1N4, Canada
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University of Laval
NOT_YET_RECRUITINGQuébec, Quebec, G1V 0B4, Canada
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University of Montreal
NOT_YET_RECRUITINGMontreal, Quebec, H3T 1J4, Canada
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University of Saskatchewan
NOT_YET_RECRUITINGSaskatoon, Saskatchewan, S7N 5A2, Canada
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University of Toronto
NOT_YET_RECRUITINGToronto, Ontario, M5S 1A1, Canada
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University of Toronto - Hospital for Sick Kids
NOT_YET_RECRUITINGToronto, Ontario, M5G 1E8, Canada
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University of Toronto - St Michael Hospital
NOT_YET_RECRUITINGToronto, Ontario, M5B 1W8, Canada
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Western University
NOT_YET_RECRUITINGLondon, Ontario, N6A 3K7, Canada
Contact
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Westmead Hospital
RECRUITINGWestmead, New South Wales, 2145, Australia
Contact
Conditions
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