University Of Louisville
Clinical trials sponsored by University Of Louisville, explained in plain language.
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New study tests better ways to fix receding gums
Disease control CompletedThis study involved 24 adults with receding gums to see if adding an enamel protein to a standard gum graft procedure improves results. The standard method uses a tissue graft placed under the gum with a small tunnel. Half the participants also got the enamel protein. Researchers…
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Which putty preserves your jawbone best? new trial tests two graft materials
Disease control CompletedThis study tested two different bone graft putties—one made from donated human bone and one synthetic—to see which better preserves the jawbone after a tooth is pulled. Thirty adults who needed a tooth removed and planned to get a dental implant took part. After 4 months, the res…
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Could a simple supplement shield you from air pollution?
Disease control CompletedThis study tests whether the dietary supplement carnosine can protect against the harmful effects of air pollution. Researchers will give 299 adults either carnosine or a placebo and measure markers of oxidative stress and heart health. The goal is to see if this natural antioxid…
Phase: NA • Sponsor: University of Louisville • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Virtual therapy helps anorexia patients face fears and stay well
Prevention CompletedThis study tested a virtual program called FED-F that helps people with anorexia nervosa face their fears about food, weight gain, body sensations, and social situations. The goal is to prevent relapse after intensive treatment. The study included 70 adults who had recently compl…
Phase: NA • Sponsor: University of Louisville • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC
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Can a phone app tame disordered eating? small study tests personalized Self-Help
Symptom relief CompletedThis study tested a self-guided smartphone program for women with disordered eating. Twenty women used their phones to track eating habits for two weeks, then received two personalized treatment modules. Researchers checked if the program was easy to use and if it helped reduce s…
Phase: NA • Sponsor: University of Louisville • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Could a muscle relaxant suppository ease chronic pelvic pain?
Symptom relief CompletedThis study tested whether a vaginal suppository containing baclofen, a muscle relaxant, can reduce pain in women with chronic pelvic pain. 39 women used either the baclofen suppository or a placebo nightly for 8 weeks. The goal was to see if pain scores improved more with the act…
Phase: PHASE2 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Breaking the loop: could stopping rumination lower blood pressure and depression?
Symptom relief CompletedThis small study tested a type of talk therapy called Rumination-Focused Cognitive Behavior Therapy (RFCBT) in 9 low-income adults who had both depressive symptoms and high blood pressure. The therapy aims to help people recognize and stop repetitive negative thoughts (rumination…
Phase: NA • Sponsor: University of Louisville • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Spinal stimulation may help bladder and blood pressure after injury
Knowledge-focused CompletedThis study looked at how spinal cord epidural stimulation affects bladder, bowel, and blood pressure control in 61 adults with spinal cord injury. Researchers monitored participants in a lab and at home to understand autonomic dysreflexia and test stimulation as a therapy. The go…
Phase: NA • Sponsor: University of Louisville • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Could a tailored approach beat standard therapy for eating disorders?
Knowledge-focused CompletedThis study compared a new personalized treatment for eating disorders (called Network-Informed Personalized Treatment) with the current standard therapy (Enhanced Cognitive Behavioral Therapy). 80 adults with eating disorders like anorexia or bulimia took part. The goal was to se…
Phase: NA • Sponsor: University of Louisville • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC