University Of Louisville
Clinical trials sponsored by University Of Louisville, explained in plain language.
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Spinal stimulation trial aims to get paralyzed patients stepping overground
Disease control OngoingThis early-phase study tests whether combining noninvasive spinal cord stimulation with a drug called buspirone can help people with severe spinal cord injury take steps overground. Fifteen participants who have been paralyzed for at least a year will undergo various training and…
Phase: EARLY_PHASE1 • Sponsor: University of Louisville • Aim: Disease control
Last updated May 15, 2026 12:02 UTC
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Spinal stimulation may help kids with paralysis regain hand grip
Disease control ENROLLING_BY_INVITATIONThis small study tests a noninvasive method called transcutaneous spinal cord stimulation (scTS) to help children aged 7-12 with chronic cervical spinal cord injury improve hand function. Researchers will try different stimulation locations and strengths on the neck and lower bac…
Phase: NA • Sponsor: University of Louisville • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New painkiller aims to replace opioids after knee surgery
Symptom relief ENROLLING_BY_INVITATIONThis study compares a new pain medicine called suzetrigine to the standard opioid oxycodone for pain after total knee replacement. About 140 adults with knee osteoarthritis will take either suzetrigine or oxycodone for two weeks after surgery. Researchers will measure pain levels…
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated May 17, 2026 02:25 UTC
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Study on magnesium for infant breathing trouble pulled before it started
Symptom relief TerminatedThis study aimed to see if a single dose of magnesium sulfate could improve breathing in infants under 12 months old with moderate to severe bronchiolitis in the intensive care unit. Researchers planned to measure changes in breathing scores and watch for side effects. However, t…
Phase: PHASE2, PHASE3 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated May 17, 2026 02:23 UTC
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Spinal stimulation may unlock better breathing for paralyzed patients
Knowledge-focused OngoingThis study looks at how spinal cord stimulation and different types of training (breathing, arm, or trunk exercises) affect lung and breathing muscle function in people with spinal cord injuries. About 36 adults with injuries at or above the T5 level will take part. The goal is t…
Phase: NA • Sponsor: University of Louisville • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC