Could a muscle relaxant suppository ease chronic pelvic pain?

NCT ID NCT05968937

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a vaginal suppository containing baclofen, a muscle relaxant, can reduce pain in women with chronic pelvic pain. 39 women used either the baclofen suppository or a placebo nightly for 8 weeks. The goal was to see if pain scores improved more with the active treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
baclofen vaginal suppository
What this could lead to
If it works, this could offer a new, non-hormonal option for managing chronic pelvic pain in women.
What could go wrong
This is a small, early-phase trial with only 39 participants. The results may not apply to everyone, and the benefit over placebo could be small or none.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ULP Female Pelvic Medicine and Reconstructive Surgery - Springs Medical Center Suite 190

    Louisville, Kentucky, 40205, United States

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