University Hospital Tuebingen
Clinical trials sponsored by University Hospital Tuebingen, explained in plain language.
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Shocking prediabetes: electric muscle training shows promise
Disease control CompletedThis pilot study tested whether whole-body electromyostimulation (WB-EMS) training can improve blood sugar control in 66 sedentary adults aged 40-65 with prediabetes. Participants were assigned to WB-EMS or control groups, and researchers measured changes in HbA1c and other healt…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Personalized weight loss: Gene-Tailored drug shows promise
Disease control CompletedThis study tested whether a drug called bromocriptine, which boosts dopamine in the brain, can help people with obesity lose weight. The key twist: the drug's effect may depend on a person's genetic makeup, specifically a gene called FTO. 120 obese adults were given either bromoc…
Phase: PHASE2 • Sponsor: University Hospital Tuebingen • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New blood test could spot fetal chromosomal issues earlier and more accurately
Diagnosis CompletedThis study tested a cell-free DNA blood test to screen for trisomy 21, 18, 13 and 22q11.2 deletion in over 1,100 pregnant women during the first trimester. The goal was to see how accurate the test is compared to standard combined screening. Researchers measured how often the tes…
Sponsor: University Hospital Tuebingen • Aim: Diagnosis
Last updated Jun 27, 2026 08:14 UTC
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Ice plant cream may shield cancer patients from chemo side effect
Prevention CompletedThis small pilot study tested whether an ice plant cream could prevent hand-foot syndrome (pain, redness, peeling on hands and feet) in 15 breast cancer patients receiving doxorubicin or docetaxel chemotherapy. The main goal was to see if a larger study is possible, not to prove …
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC
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Mind-Body program aims to ease fibromyalgia pain without drugs
Symptom relief CompletedThis study tests an 8-week program called PhYoMind, which blends physiotherapy, yoga postures, breathing exercises, and mindfulness, against home exercise alone in 40 adults with fibromyalgia. The goal is to see if the combined approach reduces disability, pain, fatigue, and stre…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jul 26, 2026 00:00 UTC
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Steering brain stimulation could ease Parkinson's symptoms
Symptom relief CompletedThis study tested two types of deep brain stimulation in 20 people with Parkinson's disease: standard omnidirectional stimulation and a newer directional steering method. The goal was to see if steering the stimulation could better control motor symptoms like muscle rigidity. Par…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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New combo therapy shows promise for stroke patients with paralyzed arms
Symptom relief CompletedThis study tested whether combining intense arm training with electrical muscle stimulation and brain stimulation could improve arm function in 20 chronic stroke survivors who had severe hand paralysis for more than 6 months. Participants received both types of brain stimulation …
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Video calls and messaging help kids transition home after mental health crisis
Symptom relief CompletedThis study tested a digital aftercare program for 60 children and teens leaving psychiatric hospital care. The program used regular video calls and a secure smartphone messenger to connect patients, parents, and teachers with their hospital therapist. The goal was to ease the ret…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Fasting may soothe aromatase inhibitor side effects
Symptom relief CompletedThis study tested whether a 7-day supervised fast (max 350 calories per day) could reduce muscle and joint pain in 54 breast cancer patients taking aromatase inhibitors. The goal was to see if fasting is feasible and improves physical well-being and quality of life. Researchers a…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Awake during breast cancer surgery? new study tests pain levels
Symptom relief CompletedThis study looked at whether using a special numbing technique (tumescent local anesthesia) during breast cancer surgery leads to less pain afterward compared to standard general anesthesia. 349 women who had breast cancer surgery took part. The goal was to see if this approach c…
Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Magnetic pulses to the brain: a new hope for depression?
Symptom relief CompletedThis study tested whether a type of brain stimulation called theta burst stimulation (TBS) can help people with major depression who haven't gotten enough relief from standard treatments. 238 adults with moderate to severe depression received either real TBS or a sham (fake) vers…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 26, 2026 17:29 UTC
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Ultrasound ruler may cut repeat breast surgeries
Knowledge-focused CompletedThis study looked at whether using a special ultrasound ruler during breast-conserving surgery helps surgeons remove all cancer the first time. Researchers reviewed records from 273 patients who had this ultrasound-guided surgery. The goal was to see if it lowered the rate of inc…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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What shapes your birth plan? over 2,600 people weigh in
Knowledge-focused CompletedThis study asked over 2,600 people, including healthcare workers and the general public, about their personal preferences for how to give birth (vaginal or cesarean). Researchers also tested whether giving extra information about things like pelvic floor health or epidurals would…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Robot or scalpel? study measures which surgery type stresses surgeons less
Knowledge-focused CompletedThis study looked at how much physical and mental stress surgeons experience during robot-assisted surgery compared to traditional laparoscopic surgery. Five trained surgeons were monitored with muscle sensors, heart rate monitors, and video recordings during routine procedures. …
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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AI learns to detect endometriosis in real time during surgery
Knowledge-focused CompletedThis completed study tested an artificial intelligence (AI) model to automatically detect endometriosis lesions in real time during laparoscopic surgery. Researchers used video recordings from 26 patients to train and validate the AI. The goal was to see if the AI could accuratel…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Robotic surgery may be easier on Surgeons' bodies
Knowledge-focused CompletedThis study measured muscle activity in surgeons performing hysterectomies with robotic assistance versus conventional laparoscopy. The goal was to see which method causes less physical strain, potentially reducing work-related injuries. Four trained surgeons participated, and the…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Robots vs. surgeons: which is better for hysterectomy?
Knowledge-focused CompletedThis study compared robot-assisted laparoscopy using the Senhance Surgical System to conventional laparoscopy for hysterectomy and other uterine surgeries. Researchers measured operating time, blood loss, and safety in 78 patients. The goal was to see if the robot offers advantag…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Hunger hormone may spark motivation in depression
Knowledge-focused CompletedThis study tested whether giving the hunger hormone ghrelin can increase dopamine release and motivation to work for rewards. Researchers used brain scans and effort tasks in 26 people (healthy volunteers and those with depression). The goal is to understand if boosting ghrelin c…
Phase: PHASE1, PHASE2 • Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Gut feeling: hunger hormone may spark motivation in depression
Knowledge-focused CompletedThis completed study tested whether giving the hunger hormone ghrelin can increase motivation and change energy use in people with major depressive disorder. 24 participants received either ghrelin or a placebo injection and then performed a task where they pressed buttons to ear…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Genetic test may help some breast cancer patients avoid unnecessary chemo
Knowledge-focused CompletedThis study looked at 270 women with early-stage, hormone-receptor-positive, HER2-negative breast cancer. Doctors used a genetic test called OncotypeDX to estimate each patient's risk of the cancer coming back. The goal was to see how the test results influenced whether patients r…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:38 UTC