University Hospital Southampton Nhs Foundation Trust

This study follows about 600 adults with Crohn's disease who are receiving ustekinumab (Stelara) as part of their routine care. The goal is to see how many achieve steroid-free remission after one year, using a standard symptom score. By including patients from both large researc…

This study tested whether a special CT scan called FFRct can help doctors better manage stable chest pain compared to standard guidelines. About 1,400 adults with chest pain but no other major heart issues took part. The goal was to see if using FFRct as the first test reduces th…

This completed trial tested whether virtual clinics offering exercise sessions and psychological support could help cancer patients maintain physical and mental health while following COVID-19 social distancing rules. Over 1,100 adults with suspected or confirmed cancer took part…

This study looks at how mepolizumab (Nucala), a treatment for severe eosinophilic asthma, impacts emotions and mental well-being in patients and their partners. Researchers will track changes in feelings like anxiety, depression, and stress using questionnaires and interviews. Th…

This study tested a digital tool that helps hospital staff identify older patients taking too many medications with anticholinergic side effects, which can cause falls, confusion, and memory issues. The tool flags high-risk patients so doctors can consider stopping or switching t…