Università Vita-salute San Raffaele

This study tests whether pirfenidone, a drug already used for lung scarring, can prevent fibrosis in patients with severe breathing failure (ARDS). About 130 adults on ventilators will receive either pirfenidone or a placebo. The goal is to see if the drug helps them spend fewer …

This study tests if adding the drug landiolol to the fluid that protects the heart during mitral valve surgery can reduce a serious complication called low cardiac output syndrome, where the heart struggles to pump enough blood after surgery. About 1500 adults having elective mit…

This study tests whether a special PET/MRI scan can accurately detect if breast cancer has spread to lymph nodes in the armpit, potentially replacing the need for surgical removal of those nodes. About 119 women with certain types of breast cancer (luminal A or lobular) will get …

This study tests whether adding ketamine to electroconvulsive therapy (ECT) helps people with severe, treatment-resistant depression feel better and have fewer memory problems. Thirty hospitalized adults will receive either ketamine or a placebo during three ECT sessions. The goa…

This study is collecting medical information and biological samples from up to 6,000 people with COVID-19. Researchers want to find out which factors predict severe illness, death, or response to treatment. The goal is to better understand the disease and help guide future care.

This study tests a new portable CPAP device designed to help people with sudden breathing failure before they reach the hospital. Researchers want to see if the device is easy enough for non-medical people to use correctly. The study involves 50 participants: healthy older adults…