Tufts Medical Center
Clinical trials sponsored by Tufts Medical Center, explained in plain language.
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Eye pain mystery: scientists probe nerve link in dry eye sufferers
Knowledge-focused TerminatedThis study looks at how common nerve-related eye pain is in people who feel discomfort in their eyes. Researchers will test 1,000 participants to see if their pain is linked to nerve issues rather than typical dry eye. The goal is to better understand these conditions, not to tes…
Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 10:43 UTC
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New video program helps native hawaiian elders share end-of-life wishes
Knowledge-focused OngoingThis study tests a video program called 'I kua na'u' to help Native Hawaiian elders aged 55 and older plan their future medical care. The program uses videos and personal recordings to make advance care planning more culturally appropriate. About 220 participants will take part i…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 12:04 UTC
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Can a simple touch test reveal hidden eye nerve damage?
Knowledge-focused TerminatedThis study aims to see if a test called quantitative sensory testing (QST) can measure how well the nerves on the eye's surface are working. Researchers will use heat, cold, and vibration on the skin near the eye to check nerve responses in people with dry eye disease or corneal …
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Video tool aims to ease tough choices for elderly kidney patients
Knowledge-focused OngoingThis study tests whether showing older patients with advanced kidney disease a video about advance care planning helps them make better medical decisions. 456 people aged 65 and older took part. The goal is to see if the video leads to more discussions and documentation of their …
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Eye scan could diagnose hidden nerve pain in dry eye patients
Knowledge-focused TerminatedThis study is testing whether a special microscope (in vivo confocal microscopy) can reliably detect tiny nerve growths called microneuromas, which may be a sign of neuropathic corneal pain. Researchers will scan the eyes of 438 adults with dry eye or corneal disease to see if th…
Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Talking computer aims to improve symptom reporting in cancer patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether a computer character that talks and gestures can help cancer patients fill out symptom surveys more completely. About 100 adults with gastrointestinal or head and neck cancer will use the system during treatment. The goal is to see if this approach reduce…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC