Eye scan could diagnose hidden nerve pain in dry eye patients
NCT ID NCT05653921
First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 19 times
Summary
This study is testing whether a special microscope (in vivo confocal microscopy) can reliably detect tiny nerve growths called microneuromas, which may be a sign of neuropathic corneal pain. Researchers will scan the eyes of 438 adults with dry eye or corneal disease to see if the presence of these microneuromas matches their pain symptoms. The goal is to validate this imaging technique as a diagnostic tool, not to provide treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Scheie Eye Institute, University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Tufts Medical Center
Boston, Massachusetts, 02111, United States
Conditions
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