Tufts Medical Center
Clinical trials sponsored by Tufts Medical Center, explained in plain language.
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Scientists test Two-Pronged attack on spreading prostate cancer
Disease control CompletedThis early-stage study tested the safety of combining two existing cancer treatments—a chemotherapy drug (docetaxel) and a bone-targeting radiation drug (radium-223)—for men with advanced prostate cancer that has spread to the bones and stopped responding to standard hormone ther…
Phase: PHASE1 • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Text messages and community support tested to fight obesity in public housing
Disease control CompletedThis study tested whether text messages about diet and exercise, combined with monthly phone calls from community health workers, could help residents of Boston public housing lose weight. Researchers compared three groups: text messages alone, text messages plus phone support, a…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New portable scan could track muscle wasting in heart patients
Diagnosis CompletedThis study tested whether a portable ultrasound machine could accurately measure muscle loss in people with heart failure. Researchers compared the ultrasound results to standard X-ray scans in 48 participants, including healthy volunteers and heart failure patients. The goal was…
Sponsor: Tufts Medical Center • Aim: Diagnosis
Last updated Apr 01, 2026 14:40 UTC
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Can a Pre-Pregnancy diet and exercise plan break the cycle of obesity for the next generation?
Prevention CompletedThis study tested whether a diet and exercise program started before pregnancy could lead to healthier babies for women with obesity. Researchers wanted to see if improving a mother's health before conception, rather than during pregnancy, could reduce the baby's body fat at birt…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Prevention
Last updated Mar 13, 2026 15:06 UTC
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Can tai chi change your gut to ease arthritis pain?
Knowledge-focused CompletedThis small, completed study explored whether mind-body exercise like Tai Chi changes gut bacteria in people with knee osteoarthritis, and if those changes relate to pain and stiffness. Researchers compared 12 weeks of Tai Chi to a wellness education program in 72 participants age…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Videos aim to give a voice to the elderly and dementia patients in critical care decisions
Knowledge-focused CompletedThis study tested whether specially trained educators using video guides could help older adults and people with dementia plan their future medical wishes while in the hospital. It involved over 11,000 patients and their caregivers at two major hospitals. The goal was to see if t…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC