Tufts Medical Center
Clinical trials sponsored by Tufts Medical Center, explained in plain language.
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Texts and coach calls help public housing residents shed pounds
Disease control CompletedThis study tested a weight management program for people living in public housing in Boston. Participants received either text messages about diet and exercise, text messages plus monthly calls from a community health worker, or no extra support. The goal was to see if the combin…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Pre-Pregnancy diet and exercise may curb obesity cycle in moms and babies
Disease control CompletedThis study tested whether starting a lifestyle program before pregnancy can improve health in obese women and their babies. Researchers enrolled 99 women who had a previous full-term pregnancy and were planning another within two years. The program focused on diet and exercise to…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New combo therapy for tough prostate cancer shows promise in early trial
Disease control CompletedThis early-phase study tested a combination of two treatments—split-dose chemotherapy (docetaxel) and a targeted radiation drug (radium-223)—in 43 men with advanced prostate cancer that no longer responds to hormone therapy. The main goal was to find the safest dose and understan…
Phase: PHASE1 • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated May 11, 2026 20:41 UTC
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Ultrasound may replace X-Ray for muscle checks in heart failure
Knowledge-focused CompletedThis study tested whether a portable ultrasound device can accurately measure muscle loss in people with heart failure, compared to the standard X-ray method. Researchers enrolled 48 participants, including healthy volunteers and heart failure patients. The goal was to see if ult…
Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 10:45 UTC
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Boston study tests walking trails and phone coaching to boost activity in low-income housing
Knowledge-focused CompletedThis study looked at whether adding walking trails, maps, and a phone-based coaching program could help people living in public housing become more physically active. Over 500 residents from 12 Boston housing developments took part and were assigned to get environmental changes, …
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 10:45 UTC
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Gut check: can Mind-Body exercise soothe arthritis?
Knowledge-focused CompletedThis study looked at how mind-body exercise (like yoga or tai chi) compares to a wellness education program in changing gut bacteria in people with osteoarthritis. 72 adults aged 55 and older with knee or hip arthritis took part. The goal was to gather information for a larger fu…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 10:39 UTC
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Videos help seniors and dementia patients make tough medical choices before it's too late
Knowledge-focused CompletedThis study tested whether showing videos to hospitalized patients aged 65 and older, or those with Alzheimer's or related dementias, helps them and their families plan future medical care. Over 11,000 patients and 600 caregivers took part at two hospitals. The goal was to see if …
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC