Tufts Medical Center

This study tested whether a healthy eating (Mediterranean diet) and exercise program started before pregnancy could help obese women lose 5-7% of their weight and improve health for both mother and baby. Researchers enrolled 99 women who had a previous baby and were planning anot…

This early-phase trial tested a combination of two drugs—docetaxel (a chemotherapy) and radium 223 (a radioactive drug)—in 43 men with advanced prostate cancer that no longer responds to hormone therapy and has spread to the bones. The main goal was to find the safest dose and wa…

This study tested if a 1-year text messaging program, with or without monthly calls from a community health worker, could help 316 public housing residents in Boston lose weight. Participants were split into three groups: text messages only, texts plus phone coaching, or a contro…

This study checks if a portable ultrasound device can accurately measure muscle and fat loss in people with heart failure. Researchers compared ultrasound results to the standard DXA scan in 48 participants, including healthy volunteers and heart failure patients. If validated, t…

This study looked at whether adding walking trails, maps, and a phone-based coaching program could help people living in public housing become more physically active. Over 500 residents from 12 Boston housing developments took part. The goal was to see if these changes helped peo…

This study tested whether showing videos about care options to hospitalized patients aged 65 and older, or those with dementia, helps them make better advance care plans. Over 11,000 patients took part at two hospitals. The goal was to see if these video discussions lead to more …

This completed study compared 12 weeks of Tai Chi to wellness education in 72 adults aged 55+ with knee osteoarthritis. Researchers looked at changes in gut bacteria and joint symptoms. The goal was to gather early data for a future larger trial, not to prove any treatment works.