Tomsk National Research Medical Center Of The Russian Academy Of Sciences

This study compares two surgical techniques to fix a leaky mitral valve caused by degenerative disease. One method replaces the tiny chords that support the valve, while the other moves existing chords to a better position. The trial will follow 64 adults for one year after surge…

This study tests whether measuring amiodarone levels in the blood helps doctors choose the right dose for people with paroxysmal atrial fibrillation (a type of irregular heartbeat). About 80 adults will receive different daily doses (100, 200, or 400 mg) and be monitored for thre…

This study is testing two different imaging techniques—SPECT and PET—to see how well they can spot brain tumors called gliomas. Forty patients with primary or recurrent glioma will receive injections of two special tracers, then undergo scans to measure how much tracer is taken u…

This early-phase trial tests a radioactive imaging agent called Technetium-99m HYNIC-FAPI in 15 people with metastatic lung, pancreas, breast, or colorectal cancer. The goal is to see how well it highlights tumors on SPECT/CT scans. Researchers will measure where the agent goes i…

This phase 2 trial is testing a new imaging agent called [99mTc]Tc-ZHER2:4107 to see how well it can detect different levels of HER2 protein in breast cancer tumors. Fifty participants will receive one injection followed by a SPECT/CT scan. The goal is to improve diagnosis and he…

This study tests a radioactive imaging agent called [99mTc]Tc-DB8 to see if it can help doctors see breast cancer tumors and tell whether they are estrogen receptor positive or negative. Forty women with primary breast cancer will get one injection of the agent, followed by a SPE…

This study looks at how high blood pressure changes the heart's structure in people who work rotating shifts in the Arctic. Researchers will track 550 workers over a year using heart ultrasounds and blood tests. The goal is to understand why some develop heart failure, not to tes…