Todd C. Lee Md Mph Fidsa

This study compares two common antibiotics, daptomycin and vancomycin, to see which one works better for adults with MRSA bloodstream infections. About 300 participants will be randomly assigned to one of the two drugs. The goal is to find which treatment leads to fewer complicat…

This phase 2 trial tests whether adding the antibiotic ertapenem to standard cefazolin treatment improves outcomes for adults with methicillin-susceptible Staphylococcus aureus bloodstream infections. About 60 participants will receive either the combination or a placebo. The stu…

This study looks at whether switching from aspirin to clopidogrel (another blood thinner) can reduce heart complications in people with a serious staph bloodstream infection. About 300 adults already taking aspirin for heart disease will be randomly assigned to stay on aspirin or…

This study is for people with a weakened immune system who have a serious lung infection called PCP. The standard treatment often causes bad side effects. Researchers want to see if a lower dose of the antibiotic TMP-SMX works just as well but with fewer side effects. About 416 a…

This study looks at 330 adults with a serious heart valve infection (prosthetic valve endocarditis) caused by S. aureus bacteria. It compares the standard approach of giving the antibiotic rifampin against not giving it, to see if skipping it is just as safe and effective. The go…