Could a lower dose of antibiotics be safer and just as effective for this lung infection?

NCT ID NCT04851015

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with a weakened immune system who have a serious lung infection called PCP. The standard treatment often causes bad side effects. Researchers want to see if a lower dose of the antibiotic TMP-SMX works just as well but with fewer side effects. About 416 adults will take part, and the study will compare the lower dose to the standard dose.

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Conditions

The condition(s) this trial relates to.

Infections Pneumocystis infectious disease pneumocystosis pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital)

    RECRUITING

    Montreal, Quebec, H4A3J1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact