Could a simple swab replace a lung scope for pneumocystis diagnosis?

NCT ID NCT06890078

Recruiting now Diagnosis Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a mouthwash or a nasal swab can accurately detect pneumocystis pneumonia (PcP) in immunocompromised patients. Currently, diagnosis often requires a bronchoscopy, which is invasive and uncomfortable. Researchers will compare the new non-invasive methods with standard tests in 240 adults with suspected PcP. If the simpler methods work well, they could make diagnosis faster and easier for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simpler, less invasive way to diagnose pneumocystis pneumonia, reducing the need for uncomfortable bronchoscopies.
What could go wrong: This is an early diagnostic study, not a treatment trial. The new methods may not be accurate enough to replace current tests, and results may not apply to all patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pneumocystosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNOCOMPROMISED PATIENTS PNEUMOCYSTIS

Contacts and locations

Locations

Hôpital Lariboisière AP-HP Maladies infectieuses
RECRUITING

Paris, France
Hôpital Saint Louis AP-HP Maladies infectieuses
RECRUITING

Paris, France
Hôpital Saint Louis AP-HP Réanimation
RECRUITING

Paris, France
Hôpital Saint-Louis AP-HP Pneumologie
RECRUITING

Paris, France

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