Tianjin Medical University Second Hospital

This trial tests whether combining two drugs—disitamab vedotin and toripalimab—with or without pelvic lymph node removal can help people with muscle-invasive bladder cancer keep their bladder. Participants, who have HER2-positive tumors and decline bladder removal surgery, will r…

This trial asks whether some people with intermediate-risk bladder cancer can safely skip chemotherapy after having their tumor removed. Doctors will use a urine test before surgery to find patients whose tumors are unlikely to shed detectable signals. These patients will then be…

This study looks at people with a very high-risk type of bladder cancer that cannot be fully removed with standard surgery. After initial treatment with immunotherapy and surgery, some patients become tumor-free. The trial then randomly assigns them to either continue immunothera…

This study compares a new surgical technique, antegrade flexible ureteroscopy-assisted PCNL, to standard PCNL for removing large, branching kidney stones (staghorn calculi). The goal is to see if the new method removes more stone fragments and causes fewer complications. The tria…