New kidney stone surgery aims for cleaner removal

NCT ID NCT07172373

Not yet recruiting Disease control Sponsor: Tianjin Medical University Second Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study compares a new surgical technique, antegrade flexible ureteroscopy-assisted PCNL, to standard PCNL for removing large, branching kidney stones (staghorn calculi). The goal is to see if the new method removes more stone fragments and causes fewer complications. The trial will enroll 420 adults across multiple centers, randomly assigning them to one of the two procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: antegrade flexible ureteroscopy-assisted PCNL (surgical procedure)
What this could lead to: If successful, this could offer a more effective and safer surgical option for removing large, branching kidney stones, potentially reducing the need for repeat procedures.
What could go wrong: This is a surgical technique study, not a new drug. The benefit may be modest, and surgery always carries risks like bleeding or infection. Results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis Staghorn Calculi urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RENAL STONES UROLITHIASIS

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Other studies related to the condition(s) this trial covers.