The University Of Texas Health Science Center At San Antonio

This phase 4 trial tests whether adding pioglitazone to an SGLT2 inhibitor (dapagliflozin) and insulin can lower blood sugar more effectively in people with type 1 diabetes while preventing a rise in ketones, which can lead to a dangerous condition called ketoacidosis. About 120 …

This study aimed to see if asking people to put down a deposit (between $30 and $100) that they could earn back by meeting their drinking goals would help them drink less. Participants would wear a remote alcohol monitor to track their drinking. The study was withdrawn before any…

This study tests whether the drug rapamycin is safe and tolerable for older adults with mild memory problems or early Alzheimer's disease. About 40 participants will take rapamycin for 12 months while researchers monitor side effects and changes in memory and thinking. The goal i…

This study was designed to test whether a program called Lifestyle MIND can help people with serious mental illness (like schizophrenia or bipolar disorder) prevent or manage type 2 diabetes. The program includes group exercise and health classes twice a week for 10 weeks. Howeve…

This phase 2 trial tests an experimental drug called IMG-7289 in 9 adults with essential thrombocythemia, a rare blood disorder causing too many platelets. The drug aims to lower platelet counts and ease symptoms. Participants take a daily pill, with doses adjusted individually. …

This study looks at whether using the Calm meditation app for 10 minutes a day can help blood cancer patients who have trouble sleeping. Researchers will track sleep, mood, and inflammation in 276 participants over 20 weeks. The goal is to find a simple, drug-free way to improve …

This study tests whether adding monthly booster sessions to standard cognitive behavioral therapy (CBT) helps people with chronic pain manage their symptoms better over 18 months. About 716 military health system beneficiaries with chronic pain will receive either standard CBT or…

This study looks at how dupilumab changes the way the nose and blood respond to house dust mites in adults with allergic asthma. Participants will be exposed to dust mites in a special chamber and receive either dupilumab or a placebo. The goal is to understand the drug's effects…

This study is gathering health information from 4,600 people in rural areas of Alabama, Kentucky, Louisiana, and Mississippi. Researchers will look for risk factors that lead to heart and lung disease. No treatments or drugs are being tested. The goal is to learn more about what …

This study looks at how middle-aged men and women lose muscle after a week of not using one leg, and how they recover with exercise. Researchers will measure muscle strength, size, and genetic activity to find sex-specific differences. The goal is to learn more so future treatmen…

This study tests a communication method to help cancer patients and the general public learn about clinical trials and make informed decisions about joining. About 581 participants will receive information to increase their awareness and positive attitudes toward trials. The goal…