The George Institute

This study tests several treatments to slow chronic kidney disease (CKD) and prevent kidney failure. About 1,000 adults with CKD will receive standard care plus one or more experimental agents. The goal is to find the best way to keep kidneys working longer and reduce the need fo…

This study compares two types of IV fluids—standard saline and a balanced solution called Plasma-Lyte 148—in adults with moderate to severe diabetic ketoacidosis (DKA) who need intensive care. The goal is to see if the balanced fluid helps patients spend more days alive and out o…

This study tests whether a drug called fludrocortisone can help people recover better after a serious type of stroke caused by a brain aneurysm rupture. About 524 critically ill adults will receive either the drug or a placebo within 96 hours of their hospital admission. The main…

This study tests whether giving a single dose of a common antibiotic soon after a breathing tube is placed can prevent lung infections (pneumonia) and improve survival in ICU patients with severe brain injuries. About 3,300 adults on ventilators due to stroke, trauma, or lack of …

This study tests two types of non-invasive brain stimulation (tDCS and rTMS) to see if they can reduce eating disorder symptoms and improve mood in people with anorexia nervosa. About 70 inpatients will receive either real or sham (fake) stimulation over 8 weeks, and be followed …