Could a simple fluid swap speed recovery from diabetic crisis?
NCT ID NCT05752279
First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 28 times
Summary
This study compares two types of IV fluids—standard saline and a balanced solution called Plasma-Lyte 148—in adults with moderate to severe diabetic ketoacidosis (DKA) who need intensive care. The goal is to see if the balanced fluid helps patients spend more days alive and out of the hospital within the first month. About 680 participants will be enrolled from emergency departments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ballarat Base Hospital
RECRUITINGBallarat, Victoria, 3350, Australia
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Blacktown Hospital
RECRUITINGBlacktown, New South Wales, 2148, Australia
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Caboolture Hospital
RECRUITINGCaboolture, Queensland, Australia
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Camperdown Hospital
RECRUITINGCamperdown, New South Wales, 2050, Australia
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Dandenong Hospital
RECRUITINGDandenong, Victoria, 3175, Australia
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Dubbo Base Hospital
RECRUITINGDubbo, New South Wales, 2830, Australia
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Frankston Hospital - Peninsula Health
RECRUITINGFrankston, Victoria, 3199, Australia
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Gold Coast University Hospital
RECRUITINGSouthport, Queensland, 4215, Australia
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Latrobe Regional Hospital
RECRUITINGTraralgon, Victoria, 3844, Australia
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Lyell McEwin Hospital
RECRUITINGElizabeth Vale, South Australia, 5112, Australia
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Maitland Hospital
RECRUITINGMetford, New South Wales, 2323, Australia
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Monash Health-Casey Hospital
RECRUITINGBerwick, Victoria, 3806, Australia
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Orange Hospital
RECRUITINGOrange, New South Wales, 2800, Australia
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Queen Elizabeth II Jubilee Hospital
RECRUITINGCoopers Plains, Queensland, 4108, Australia
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Redcliffe Hospital
RECRUITINGRedcliffe, Queensland, 4020, Australia
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Rockhampton Hospital
RECRUITINGRockhampton, Queensland, 4700, Australia
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Royal North Shore Hospital
RECRUITINGSt Leonards, New South Wales, 2065, Australia
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St George Hospital
RECRUITINGKogarah, New South Wales, 2217, Australia
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Sunshine Coast University Hospital
RECRUITINGBirtinya, Queensland, 4575, Australia
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The Queen Elizabeth Hospital
RECRUITINGWoodville South, South Australia, 5011, Australia
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Westmead Hospital
RECRUITINGWestmead, New South Wales, 2145, Australia
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Conditions
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