Gene hunt aims to prevent deadly diabetes drug complication

NCT ID NCT05402579

First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 14 times

Summary

This study looked at whether a person's genes can help predict their risk of diabetic ketoacidosis (DKA), a life-threatening side effect of SGLT2 inhibitor drugs used for type 2 diabetes. Researchers compared the DNA of 63 patients who had DKA while on the drug to those who did not. The goal is to find genetic markers that could help doctors identify who is most at risk, so they can use these beneficial drugs more safely.

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Contacts and locations

Locations

  • St. Joseph's Health Centre (Unity Health Toronto)

    Toronto, Ontario, Canada

  • Toronto General Hospital (University Health Network)

    Toronto, Ontario, Canada

Conditions

Explore the condition pages connected to this study.