Could a simple vitamin speed recovery from a dangerous diabetes complication?

NCT ID NCT03717896

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether giving intravenous thiamine (vitamin B1) alongside standard treatment helps people with diabetic ketoacidosis recover faster. Diabetic ketoacidosis is a serious condition where the blood becomes too acidic. The study includes adults hospitalized with this condition and compares thiamine to a placebo. Researchers will measure how quickly acidosis resolves and whether hospital stays are shortened.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

thiamine (vitamin B1)

What this could lead to

If it works, this could speed up recovery from diabetic ketoacidosis and reduce hospital stays.

What could go wrong

This is a small Phase 2 trial, so results may not be conclusive. Thiamine is generally safe, but it may not provide added benefit over standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acidosis diabetic ketoacidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States